How scorpion venom (and Prometheus) are used to understand pain protein structure
Voltage-gated sodium channels, or Navs, are responsible for initiating and propagating action potentials in excitable…
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3 ways MST has improved cell signaling research
Just as humans talk, dogs bark, and insects produce pheromones, cells have their own communication…
Scientists reveal new mechanism of gene regulation by sRNA in Archaea
“Wolfe, these things aren’t even bacteria!!” It was about four decades ago when Carl Woese,…
Mystery solved. A protein’s unfolded intermediates can bind to ligands and impact affinity
The native state of a protein is not one single conformation, but an ensemble of…
MST proves to be an essential tool for SAR study aimed at using apoptosis to fight cancer
Developing and taking a drug to market is a long and expensive path: on average…
Label-free MST takes a deeper look at bacteria’s vulnerable site and reveals potential druggable target
A group from the University of Gothenburg recently published a functional characterization of a bacterial…
In the wild! Characterizing protein variants in native environment uncovers risk for large artery atherosclerotic stroke
Proteins don’t always behave the way they do in their natural environment when studied in…
Why being highly sensitive is a good thing – Measuring RNA-ligand binding interactions using less sample
RNA molecules come in different shapes and sizes and regulate all kinds of biological processes.…
In science we trust!…Wait, do we?
So much of scientific work is irreproducible. Why is that? What can be done to…