Label-free MST takes a deeper look at bacteria’s vulnerable site and reveals potential druggable target
A group from the University of Gothenburg recently published a functional characterization of a bacterial…
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In the wild! Characterizing protein variants in native environment uncovers risk for large artery atherosclerotic stroke
Proteins don’t always behave the way they do in their natural environment when studied in…
Why being highly sensitive is a good thing – Measuring RNA-ligand binding interactions using less sample
RNA molecules come in different shapes and sizes and regulate all kinds of biological processes.…
In science we trust!…Wait, do we?
So much of scientific work is irreproducible. Why is that? What can be done to…
Microscale Thermophoresis generated Kd values for Affimer proteins surpassing pitfalls of other technologies
Affimers are a good alternative to antibodies — they’re small engineered binding proteins that possess…
MicroScale Thermophoresis makes it possible to measure binding affinity of Nanobodies under the harshest conditions
Antibodies are widely recognized as the gold standard for biological recognition, but unfortunately these molecules…
ChromoTek uses Prometheus and discovers the extraordinary stability of their GBP:GFP complex
Although traditional IgG antibodies are often used for immunoprecipitation and protein interaction analysis, GFP-binding protein…
MST Delivers Exclusive Hits in Fragment-Based Screening Campaigns
A new study by Boehringer Ingelheim shows that MST is particularly well suited for fragment-based…
A Winning Team: Stability and Functionality of DNA Binding Proteins
In the journal Nucleic Acids Research, a study has been published by de Lange et…