Is the protein folding mystery close to being solved?
It takes a lot more than several amino acids joined together to obtain a functional…
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Fragment-based screening using MST and NMR leads to discovery of IDO1 inhibitor
Cut, burn and poison (meaning surgery, radiation therapy and chemotherapy) have been the traditional and…
NanoTemper awarded the German Physical Society Technology Transfer Prize
The German Physical Society (DPG), the world’s largest organization of physicists whose previous presidents include…
Scientists reveal new mechanism of gene regulation by sRNA in Archaea
“Wolfe, these things aren’t even bacteria!!” It was about four decades ago when Carl Woese,…
Answering the demands for a new screening tool for drug discovery with Dianthus
There’s a gap that exists in screening tools for drug discovery — the need for…
How Proteros thrives in the legacy of a Nobel Laureate founder while applying innovative methods for hit to lead discovery
If you work for a company that’s been around for 20 years and was co-founded…
Introducing Monolith NT.115 mini, measure binding affinity anywhere
In the past few years, there’s been a number of articles touting the benefits of…
Mystery solved. A protein’s unfolded intermediates can bind to ligands and impact affinity
The native state of a protein is not one single conformation, but an ensemble of…
3 ways to know your protein purification is a success
Protein purification is a challenging endeavor for many scientists and it usually takes time and…