Chinese Academy of Sciences – Liu Qingsong

We use MicroScale Thermophoresis (MST) to measure the affinity of our compounds, aptamers, and nanodiscs to their targets. Using this technology, we obtained very convincing data that were in good agreement with results obtained from ITC and NMR. Its advantages include low material consumption, short measurement times, immobilization-free setup, maintenance-free instrumentation, and a wide range of accessible interactions. MST is mainly used as an easy and fast approach for the characterization of interactions.


 

Prof. Liu Qingsong
High Magnetic Field Laboratory
Chinese Academy of Sciences
China