Our main focus is looking for small molecular inhibitors for receptors like PD-L1. We have found MST to be useful to determine drug potency due to its versatility and low sample size requirement. The results correlate nicely with the ones obtained from other techniques (HTRF and Fluorescence Polarization Assays), but thanks to an instrument with low complexity like Monolith, we find MST to be more reliable. Lastly, I’d like to highlight the software as very user friendly, with an interface that guides you through the whole procedure and readily analyses the results.
Dr. Jacek Plewka
Jagiellonian University, Department of Chemistry