NanoTemper’s Prometheus is an excellent equipment for studying the Tm of any protein. It is comparable to DSC but is high throughput. Another advantage is that the analysis requires very small sample volume, negligible effort in sample preparation as even no dilution is required for concentrations of up to ~200 mg/mL in turn providing a broad concentration range for analysis. In addition to this, we can analyze 25 samples in less than 2 hours.
Senior Research Scientist
Product Characterization Team