We use MST to verify interactions between aptamers and proteins for drug development, and in the future, we plan to expand its use to study interactions between aptamers and small molecules. The reason why we were interested in MST in the first place was that we needed a method that required less amount of protein as they can be really expensive for us. Additionally, it provides very fast time to results, allowing us to analyze large batches of aptamers in relatively short time.
Dr. Anna Varizhuk
Research and Clinical Center of Physical-Chemical Medicine