MicroScale Thermophoresis (MST) is an in-solution, contact-free biophysical technology for protein-protein, protein-DNA and protein-small molecule interactions characterization. Label-Free MST allows to study biomolecules without disturbances by labeling or surfacing, and only requires little protein consumption and very short processing time. We are using this technology to determine the interactions between drug target protein and small molecules that have significant fluorescence interferences with other method and have obtained perfect results. We highly recommend MST for efficient and reliable quantification of biomolecule interactions in drug discovery.
Professor Liang Zhang
College of Basic Medical Sciences
Shanghai Jiao Tong University