Hello, we’re NanoTemper!
We create biophysical tools that give scientists the clarity, confidence, and momentum they need to discover future therapies — even difficult ones.
At NanoTemper, we have one clear goal: a world where every disease is treatable.
This vision drives us to empower scientists with biophysical solutions they trust, helping them solve their toughest challenges and ultimately discover life-saving therapies.
As a 100% founder-owned company, we are continuously pioneering groundbreaking ideas, redefine what’s possible, and push boundaries. Innovation is in our DNA, driving our commitment to precision, uncompromising quality, and strong, collaborative partnerships with our customers.
We develop the highest-quality instruments, delivering reliable and precise results. Made to be easy-to-learn, easy-to-use, and automation-ready, our solutions streamline workflows while increasing efficiency. We support our customers with in-depth knowledge and scientific expertise at every stage of their journey, ensuring they achieve their goals.
Since 2008, leading pharmaceutical companies, biotech, and research institutions have relied on our solutions to accelerate drug development. And this was just our beginning:
With our end-to-end, GMP-compliant solutions we’re quickly advancing into biomanufacturing supporting the entire drug development process—from discovery to release.
It’s a long path to a world where every disease is treatable, and it demands bold thinking, determination, and collaboration.
At NanoTemper, we’re ready for this challenge.
Join us on this journey. Let’s make an impact together.
Where our customers need us
At NanoTemper, we’ve expanded our team, our locations, and our network of distributors to best serve the needs of our customers.
We’re headquartered in Munich, Germany with representation in countries around the world including the United Kingdom, Poland, France, United States, Japan, China, and India.
400 Oyster Point Blvd. Suite 336
South San Francisco, CA 94080
United States
9 Galen St. Suite 317A
Watertown, MA 02472
United States
20 Wellington Street East, Suite 500
Toronto, ON, M5E 1C5
Canada
Flößergasse 4
81369 München
Germany
Room 1609-1611,
Beijing Fortune Building, No. 5
North Dongsanhuan Road,
Chaoyang District
100004 Beijing
China
Room 1858, Bund Center,
222 Yan’an East Road
Huangpu District
200120 Shanghai
China
Level 19, Minato Mirai Center Building,
3-6-1, Minato mirai, Nishi-ku, Yokohama-shi,
Kanagawa 220-0012
Japan
World Trade Center, 22nd Floor
Brigade Gateway Campus,
Malleswaram (W)
Bangalore-560055
India
Life Science Park
ul.Bobrzyńskiego 14
30-348 Kraków
Poland
What’s new from NanoTemper
NanoTemper Technologies announces Monolith X with breakthrough Spectral Shift technology, enabling binding affinity measurements where other methods fail
NanoTemper Technologies launches Spectral Shift, a breakthrough technology that changes the game for affinity-based screenings
NanoTemper Technologies launches DLS capability with Prometheus Panta, bringing high-resolution, domain-specific stability characterization to biologics
We’re scientists ourselves
The values that guide us
Our values guide our work, our culture, and our commitment to help customers solve their biggest challenges.
Curosity
We ask difficult questions to find clarity. We learn continuously and stay open-minded to be creative, bold, and innovative.
Impact
We share a sustainable high-performance mindset. We keep current and future customers at the core of our actions. Our contribution to their success makes a tangible difference and leaves a meaningful footprint.
We-Power
With mutual trust, empathy and appreciation, we create a safe environment that releases our full potential. We are candid, encouraging, respectful, and truly care for each other.
Moving science forward is in our DNA
Stefan Duhr and Philipp Baaske, NanoTemper’s co-founders, set out to build a company to address challenges researchers were facing with the ultimate goal of helping to move science forward.
NanoTemper was started in 2008 after they met at Ludwig-Maximilians-University Munich. At the time, the effect of thermophoresis was not known within the Life Sciences community, but Stefan and Philipp knew that it was important. Realizing the shortcomings of current protein research techniques, they came up with a method, MicroScale Thermophoresis that was enormously sensitive, and would bring researchers one step closer to developing better drugs faster.
Overcome your drug discovery challenges
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Prometheus
Select ideal candidates with high-resolution stability data -
Dianthus
Screen and validate hits for challenging targets -
Monolith
Measure binding affinities in solution
Prometheus
Prometheus
Measure conformational and colloidal stability in a single experiment to learn which constructs and buffer conditions are most ideal for preserving the integrity of your biologic therapeutics. Feel confident you’re selecting the best candidates with high-resolution data from Prometheus Panta.
Dianthus
Dianthus
Dianthus is a plate-based affinity screening platform that finds binding affinities in solution and delivers high-quality binding data with less assay development.
Get an affinity screening solution that avoids the pitfalls of immobilization for your fragment libraries, intrinsically disordered proteins, or PROTAC binary and ternary complexes. Screen hundreds of compounds in less time than alternative methods, and ensure you’re finding all your hits with Dianthus with Spectral Shift technology.
Monolith
Monolith
Monolith enables you to measure the strength of molecular interactions in solution using minimal sample.
Trust an orthogonal tool to validate your binding results from other methodologies, or to get a Kd in challenging situations where other methods failed. With ultra-low sample consumption and versatile applications – including protein-protein interactions, small molecule affinities, and nucleic acid binding – Monolith is the best solution for your binding affinity experiments.
Join the NanoTemper team
Everyone at NanoTemper, in every department, contributes to giving our customers momentum to discover and develop therapies. If you’re looking to make a big impact in a collaborative setting, NanoTemper is the place for you.
