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Monolith Pico
The best choice for studying interactions spanning a broad range of sensitivity. Turn pico mode on to measure very strong interactions, or off for weak ones.
Monolith
Choose this if you want the most flexibility when it comes to labeling strategy. Pick the two fluorescent channels you need the most.
Monolith LabelFree
When you just want to measure interactions by detecting the intrinsic fluorescence of your target protein.
Time it takes to get a Kd
10 minutes or less (standard mode for binding affinity)
Dynamic range
1 pM to mM
1 nM to mM
10 nM to mM
Detected molecule range
101–107 Daltons
Minimum sample volume measured
4 μL
Samples per run
Up to 24
Temperature control
20-40 °C +/- 0.5 °C (actively controlled)
Fluorescent channels
1 (pico RED) or
2 (pico RED & LabelFree (UV) or
pico RED & BLUE)
2 (RED & LabelFree (UV),
RED & BLUE, RED & GREEN or
BLUE & GREEN)
1 (LabelFree (UV))
Dimensions
36 cm W x 40 cm H x 58 cm D (71 cm D with drawer open)
Weight
27 kg