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Find the consumables and kits you need for your Monolith

Only the highest quality products

Ensuring that customers always have the best quality products is at the top of our list. We pay special attention to the capillaries—they’re manufactured in a state-of-the-art facility following the same stringent protocols used for diagnostic-grade capillaries and rigorously tested. With over 10 years of experience, we’re proud that our patented capillary technology minimizes undesirable effects to proteins, while delivering the quality and consistency associated with NanoTemper Technologies.
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Monolith Control Kits

Catalog #
Product
Description
MO-C030

MO-C030

Monolith NT.115 Control Kit RED
Monitor the performance of the Monolith, or use when operating the system for the first time or when training new users. For Nano-GREEN/RED or Nano-BLUE/RED or Pico-RED detectors.
MO-C032

MO-C032

Monolith NT.LabelFree Control Kit
Monitor the performance of the Monolith, or use when operating the system for the first time or when training new users. For LabelFree detectors.

Spectral Shift Optimized Protein Labeling Kits

Catalog #
Product
Description
NT-L021

NT-L021

Spectral Shift Optimized Protein Labeling Kit – Lysine-Reactive (Size L)

The Spectral shift Optimized Labeling Kits are designed to enhance the capabilities of Spectral shift systems, these kits deliver faster labeling, higher dye affinities, and up to 3 times less sample consumption This advanced, Lysine-reactive kit offers a rapid and efficient method for covalently labeling primary amines, particularly lysine residues It contains all required reagents for labeling and dye removal. The dye carries a reactive NHS-ester group that reacts with primary amines (lysine residues) to form a covalent bond. The kit is optimized for proteins with a molecular weight higher than 5 kDa and concentrations between 2 and 20 µM

The kit contains material sufficient for 4 independent labeling reactions.

NT-L024

NT-L024

Spectral Shift Optimized Protein Labeling Kit – Cysteine-Reactive (Size L)

The Spectral shift Optimized Labeling Kits are designed to enhance the capabilities of Spectral shift systems, these kits deliver faster labeling, higher dye affinities, and up to 3 times less sample consumption This advanced, Cysteine-reactive kit offers a rapid and efficient method for covalently labeling thiols, particularly cysteine residues.

The kit is optimized for labeling and purification of proteins with a molecular weight higher than 5 kDa.

The kit contains material sufficient for 4 independent labeling reactions.

NT-L028

NT-L028

Spectral Shift Optimized Protein Labeling Kit – For His-Tag (Size M)

The Spectral shift Optimized Labeling Kits are designed to enhance the capabilities of Spectral shift systems, these kits deliver faster labeling, higher dye affinities, and up to 3 times less sample consumption  This kit provides convenient means for the site-specific, purification-free labeling of small amounts of His-tagged Proteins.
It can be used for the labeling of any protein or peptide carrying a polyhistidine-tag (His-tag) which contain at least six histidines with a Kd in the single digit nanomolar range.

The kit contains material sufficient for 500 data points.

NT-L128

NT-L128

Spectral Shift Optimized Protein Labeling Kit – For His-Tag (Size L)

The Spectral shift Optimized Labeling Kits are designed to enhance the capabilities of Spectral shift systems, these kits deliver faster labeling, higher dye affinities, and up to 3 times less sample consumption

This kit provides convenient means for the site-specific, purification-free labeling of small amounts of His-tagged Proteins.
It can be used for the labeling of any protein or peptide carrying a polyhistidine-tag (His-tag) which contain at least six histidines with a Kd in the single digit nanomolar range. The kit contains material sufficient for 4,000 data points.

2nd Generation Protein Labeling Kits

Catalog #
Product
Description
MO-L011

MO-L011

Protein Labeling Kit RED-NHS 2nd Generation (Amine Reactive)
The Monolith Protein Labeling Kit RED-NHS 2nd Generation kit increases data quality and enables affinity studies with previously challenging targets by generating higher binding amplitudes and improved signal-to-noise ratios. It contains all required reagents for labeling and dye removal. The dye carries a reactive NHS-ester group that reacts with primary amines (lysine residues) to form a covalent bond. The kit is optimized for proteins with a molecular weight higher than 5 kDa and concentrations between 2 and 20 µM. RED dyes are suited for Monolith instruments with a RED detector (Nano and Pico) and Dianthus instruments.
MO-L014

MO-L014

Protein Labeling Kit RED-MALEIMIDE 2nd Generation (Cysteine reactive)
The Monolith Protein Labeling Kit RED-MALEIMIDE 2nd Generation kit increases data quality and enables affinity studies with previously challenging targets by generating higher binding amplitudes and improved signal-to-noise ratios. It contains all required reagents for labeling and dye removal. The dye carries a reactive maleimide group that reacts with cysteine residues to form a covalent bond. The kit is optimized for proteins with a molecular weight higher than 5 kDa and concentrations between 2 and 20 µM. RED dyes are suited for Monolith instruments with a RED detector (Nano and Pico) and Dianthus instruments.
MO-L018

MO-L018

His-Tag Labeling Kit RED-tris-NTA 2nd Generation
The Monolith His-Tag Labeling Kit RED-tris-NTA 2nd Generation kit increases data quality and enables affinity studies with previously challenging targets by generating higher binding amplitudes and improved signal-to-noise ratios. The kit is used for site-specific and purification-free labeling of His-tagged (6xHis) proteins and peptides. The kit can be used with purified as well as crude samples (e.g. cell lysate) and contains material sufficient for 500 single-point MST measurements. RED dyes are suited for Monolith instruments with a RED detector (Nano and Pico) and Dianthus instruments.
MO-L019

MO-L019

SNAP-Tag® Labeling Kit RED 2nd Generation
The SNAP-Tag® Labeling Kit RED 2nd Generation contains all required reagents for labeling and dye removal. The dye carries a benzylguanine group that reacts with the SNAP-tag® of your protein of interest to form a covalent bond. The kit is optimized for protein concentrations of 10 µM. Just like all of our 2nd Generation labeling kits, it increases data quality and enables affinity studies with previously challenging targets by generating higher binding amplitudes and improved signal-to-noise ratios. RED dyes are suited for Monolith instruments with a RED detector (Nano and Pico) and Dianthus instruments. Contents require storage at 4 °C and -20 °C.
NT-L111

NT-L111

Large Volume Protein Labeling Kit RED-NHS 2nd Generation (Amine Reactive)
This Large Volume Protein Labeling Kit RED-NHS 2nd Generation kit increases data quality and enables affinity studies with previously challenging targets by generating higher binding amplitudes and improved signal-to-noise ratios. It contains all required reagents for labeling and dye removal. The dye carries a reactive NHS-ester group that reacts with primary amines (lysine residues) to form a covalent bond. The kit is optimized for proteins with a molecular weight higher than 5 kDa and concentrations between 2 and 20 µM. RED dyes are suited for Monolith instruments with a RED detector (Nano and Pico) and Dianthus instruments. Contents require storage at 4 °C and -20 °C.
NT-L114

NT-L114

Large Volume Protein Labeling Kit RED-MALEIMIDE 2nd Generation (Cysteine reactive)
This Large Volume Protein Labeling Kit RED-MALEIMIDE 2nd Generation kit increases data quality and enables affinity studies with previously challenging targets by generating higher binding amplitudes and improved signal-to-noise ratios. It contains all required reagents for labeling and dye removal. The dye carries a reactive maleimide group that reacts with cysteine residues to form a covalent bond. The kit is optimized for proteins with a molecular weight higher than 5 kDa and concentrations between 2 and 20 µM. RED dyes are suited for Monolith instruments with a RED detector (Nano and Pico) and Dianthus instruments. Contents require storage at 4 °C and -20 °C.
NT-L118

NT-L118

Large Volume His-Tag Labeling Kit RED-tris-NTA 2nd Generation
This Large Volume His-Tag Labeling Kit RED-tris-NTA 2nd Generation kit increases data quality and enables affinity studies with previously challenging targets by generating higher binding amplitudes and improved signal-to-noise ratios. The kit is used for site-specific and purification-free labeling of His-tagged (6xHis) proteins and peptides. The kit can be used with purified as well as crude samples (e.g. cell lysate) and contains material sufficient for 3840 single-point MST measurements. RED dyes are suited for Monolith instruments with a RED detector (Nano and Pico) and Dianthus instruments. Store at -20 °C.
NT-L020

NT-L020

Biotinylated Target Labeling Kit
The Biotinylated Target Labeling Kit is used for the site-directed labeling of any protein or peptide carrying one or multiple biotin tags. It contains material sufficient for labeling 500 single-point spectral shift measurements. The kit includes a protocol for labeling in 15 min with no removal of excess dye required. The Biotinylated Target Labeling Kit is suited for use with Monolith X and Dianthus with Spectral Shift. Contents require storage at -20 °C.
NT-L120

NT-L120

Large Volume Biotinylated Target Labeling Kit
The Large Volume Biotinylated Target Labeling Kit is used for the site-directed labeling of any protein or peptide carrying one or multiple biotin tags. It contains material sufficient for labeling 4,000 single-point spectral shift measurements. The kit includes a protocol for labeling in 15 min with no removal of excess dye required. The Large Volume Biotinylated Target Labeling Kit is suited for use with Monolith X and Dianthus with Spectral Shift. Contents require storage at -20 °C.
NT-L030

NT-L030

Small Volume Human Fc Labeling Kit
The Small Volume Human Fc Labeling Kit provides a convenient means for the site-specific, purification-free labeling of humanized antibodies or antibody fragments containing the Fc region with fluorescent dye optimized for affinity measurements done with Spectral Shift technology. The kit is used for the site-directed labeling of any protein carrying a Human Fc antibody region. It contains material sufficient for labeling for 500 single-point Spectral Shift measurements. The kit includes a protocol for labeling in <30 min; no removal of excess dye required. The Small Volume Human Fc Labeling Kit is suited for use with Monolith X and Dianthus with Spectral Shift. Contents require storage at -20 °C.
NT-L130

NT-L130

Large Volume Human Fc Labeling Kit
The Large Volume Human Fc Labeling Kit provides a convenient means for the site-specific, purification-free labeling of humanized antibodies or antibody fragments containing the Fc region with fluorescent dye optimized for affinity measurements done with Spectral Shift technology. The kit is used for the site-directed labeling of any protein carrying a Human Fc antibody region. It contains material sufficient for labeling for 4,000 single-point Spectral Shift measurements. The kit includes a protocol for labeling in <30 min; no removal of excess dye required. The Large Volume Human Fc Labeling Kit is suited for use with Monolith X and Dianthus with Spectral Shift. Contents require storage at -20 °C.

Assay Development Kits

Catalog #
Product
Description
NT-B001

NT-B001

Buffer Exploration Kit
Your mission is to find the right buffer conditions for biophysical interaction assays, protein stability, purification, and storage. This kit will help you with your MST and TRIC assay development. Start your buffer exploration with this 96 deep-well plate containing 1 mL of each buffer condition per well.
MO-X001

MO-X001

Monolith Explorer Kit – Mission to Mars
The goal of this mission is to get your assay development going. We’ve packed everything you’ll need to perform one independent labeling reaction for proteins and peptides with RED-NHS and RED-tris-NTA 2nd Generation dyes. Includes dyes, dye removal reagents, and 60 premium capillaries. Store contents at room temperature, 4 °C and -20 °C as required.

Monolith Capillaries

Catalog #
Product
Description
MO-AK002

MO-AK002

Monolith NT.Automated Capillary Chips
High precision glass capillaries for Monolith NT.Automated. Includes 16 chips, 24 capillaries per chip. Enough chips to measure 384 data points. Store at room temperature.
MO-AK005

MO-AK005

Monolith NT.Automated Premium Capillary Chips
High precision glass capillaries for Monolith NT.Automated, covalently coated with a specially designed polymer. Includes 16 chips, 24 capillaries per chip. Enough chips to measure 384 data points. Store at room temperature.
MO-AZ005

MO-AZ005

Monolith NT.Automated LabelFree Premium Capillary Chips
High precision glass capillaries for label-free assays in Monolith NT.Automated, covalently coated with a specially designed polymer. Includes 16 chips, 24 capillaries per chip. Enough chips to measure 384 data points. Store at room temperature.
MO-K022

MO-K022

Monolith NT.115 Capillaries
High precision capillary geometry, physically treated to obtain high quality surface properties. 1000 capillaries for the Monolith NT.115 systems are included.
MO-K025

MO-K025

Monolith NT.115 Premium Capillaries
High precision capillary geometry, covalently coated with a specially designed polymer to prevent surface adsorption of molecules. 200 Premium Capillaries for the Monolith NT.115 systems are included.
MO-Z022

MO-Z022

Monolith NT.LabelFree Capillaries
High precision capillary geometry, physically treated to obtain high quality surface properties and low background signal. 200 capillaries for Monolith NT.LabelFree system are included.
MO-Z025

MO-Z025

Monolith NT.LabelFree Premium Capillaries
High precision capillary geometry, covalently coated with a specially designed polymer to prevent surface adsorption of molecules. 200 Premium Capillaries for the NT.LabelFree instruments are included.
MO-MK025

MO-MK025

Monolith Premium Capillary Chips
Premium Capillary Chips for Monolith instruments. The capillary surface is covalently coated with a dense brush of a specially designed polymer to keep sticky proteins free in solution for analysis. Includes 2 boxes, each containing 8 chips of 24 capillaries each. To be used with the Monolith Premium Capillary Chip Lid (CAT# MO-T022). Not suitable for Monolith NT.115.
MO-MZ025

MO-MZ025

Monolith LabelFree Premium Capillary Chips
Premium LabelFree Capillary Chips for Monolith LabelFree instruments. The capillary surface is covalently coated with a dense brush of a specially designed polymer to keep sticky proteins free in solution for analysis. Includes 2 boxes, each containing 8 chips of 24 capillaries each. To be used with the Monolith Premium Capillary Chip Lid (CAT# MO-T022). Not suitable for Monolith NT.115.

Monolith Accessories

Catalog #
Product
Description
MO-T001

MO-T001

Premium Capillary Tray Monolith NT.115 Series
Premium Capillary Tray for up to 16 capillaries for the Monolith NT.115 and NT.115Pico systems.
MO-T002

MO-T002

Premium Capillary Tray Monolith NT.LabelFree
Premium Capillary Tray for up to 16 capillaries for the Monolith NT.LabelFree system.
MO-T021

MO-T021

Premium Capillary Tray Monolith
Additional capillary tray for loading samples for Monolith measurements.
MO-T022

MO-T022

Monolith Premium Capillary Chip Lid
This additional capillary chip lid is specifically designed for Monolith and is required to employ Monolith Capillary Chips in the instrument. Suitable for Monolith and Monolith LabelFree Premium Capillary Chips. Not suitable for Monolith NT.115 or Monolith NT.LabelFree.
NT-AT100

NT-AT100

Capillary Chip Filling Station
Facilitates manual filling of capillary chips from microtiter plates or from individual tubes.
Gradient spot

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