Only the highest quality products

Ensuring that customers always have the best quality products is at the top of our list. We pay special attention to the capillaries—they’re manufactured in a state-of-the-art facility following the same stringent protocols used for diagnostic-grade capillaries and rigorously tested. With over 10 years of experience, we’re proud that our patented capillary technology minimizes undesirable effects to proteins, while delivering the quality and consistency associated with NanoTemper Technologies.

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Monolith Control Kits

Catalog #

MO-C030

Product

Monolith NT.115 Control Kit RED

Description

Monitor the performance of the Monolith, or use when operating the system for the first time or when training new users. For Nano-GREEN/RED or Nano-BLUE/RED or Pico-RED detectors.

MO-C032

Monolith NT.LabelFree Control Kit

Monitor the performance of the Monolith, or use when operating the system for the first time or when training new users. For LabelFree detectors.

2nd Generation Protein Labeling Kits

Catalog #

MO-L011

Product

Protein Labeling Kit RED-NHS 2nd Generation (Amine Reactive)

Description

The Monolith Protein Labeling Kit RED-NHS 2nd Generation kit increases data quality and enables affinity studies with previously challenging targets by generating higher binding amplitudes and improved signal-to-noise ratios. It contains all required reagents for labeling and dye removal. The dye carries a reactive NHS-ester group that reacts with primary amines (lysine residues) to form a covalent bond. The kit is optimized for proteins with a molecular weight higher than 5 kDa and concentrations between 2 and 20 µM. RED dyes are suited for Monolith instruments with a RED detector (Nano and Pico) and Dianthus instruments.

MO-L014

Protein Labeling Kit RED-MALEIMIDE 2nd Generation (Cysteine reactive)

The Monolith Protein Labeling Kit RED-MALEIMIDE 2nd Generation kit increases data quality and enables affinity studies with previously challenging targets by generating higher binding amplitudes and improved signal-to-noise ratios. It contains all required reagents for labeling and dye removal. The dye carries a reactive maleimide group that reacts with cysteine residues to form a covalent bond. The kit is optimized for proteins with a molecular weight higher than 5 kDa and concentrations between 2 and 20 µM. RED dyes are suited for Monolith instruments with a RED detector (Nano and Pico) and Dianthus instruments.

MO-L018

His-Tag Labeling Kit RED-tris-NTA 2nd Generation

The Monolith His-Tag Labeling Kit RED-tris-NTA 2nd Generation kit increases data quality and enables affinity studies with previously challenging targets by generating higher binding amplitudes and improved signal-to-noise ratios. The kit is used for site-specific and purification-free labeling of His-tagged (6xHis) proteins and peptides. The kit can be used with purified as well as crude samples (e.g. cell lysate) and contains material sufficient for 500 single-point MST measurements. RED dyes are suited for Monolith instruments with a RED detector (Nano and Pico) and Dianthus instruments.

MO-L019

SNAP-Tag® Labeling Kit RED 2nd Generation

The SNAP-Tag® Labeling Kit RED 2nd Generation contains all required reagents for labeling and dye removal. The dye carries a benzylguanine group that reacts with the SNAP-tag® of your protein of interest to form a covalent bond. The kit is optimized for protein concentrations of 10 µM. Just like all of our 2nd Generation labeling kits, it increases data quality and enables affinity studies with previously challenging targets by generating higher binding amplitudes and improved signal-to-noise ratios. RED dyes are suited for Monolith instruments with a RED detector (Nano and Pico) and Dianthus instruments. Contents require storage at 4 °C and -20 °C.

NT-L111

Large Volume Protein Labeling Kit RED-NHS 2nd Generation (Amine Reactive)

This Large Volume Protein Labeling Kit RED-NHS 2nd Generation kit increases data quality and enables affinity studies with previously challenging targets by generating higher binding amplitudes and improved signal-to-noise ratios. It contains all required reagents for labeling and dye removal. The dye carries a reactive NHS-ester group that reacts with primary amines (lysine residues) to form a covalent bond. The kit is optimized for proteins with a molecular weight higher than 5 kDa and concentrations between 2 and 20 µM. RED dyes are suited for Monolith instruments with a RED detector (Nano and Pico) and Dianthus instruments. Contents require storage at 4 °C and -20 °C.

NT-L114

Large Volume Protein Labeling Kit RED-MALEIMIDE 2nd Generation (Cysteine reactive)

This Large Volume Protein Labeling Kit RED-MALEIMIDE 2nd Generation kit increases data quality and enables affinity studies with previously challenging targets by generating higher binding amplitudes and improved signal-to-noise ratios. It contains all required reagents for labeling and dye removal. The dye carries a reactive maleimide group that reacts with cysteine residues to form a covalent bond. The kit is optimized for proteins with a molecular weight higher than 5 kDa and concentrations between 2 and 20 µM. RED dyes are suited for Monolith instruments with a RED detector (Nano and Pico) and Dianthus instruments. Contents require storage at 4 °C and -20 °C.

NT-L118

Large Volume His-Tag Labeling Kit RED-tris-NTA 2nd Generation

This Large Volume His-Tag Labeling Kit RED-tris-NTA 2nd Generation kit increases data quality and enables affinity studies with previously challenging targets by generating higher binding amplitudes and improved signal-to-noise ratios. The kit is used for site-specific and purification-free labeling of His-tagged (6xHis) proteins and peptides. The kit can be used with purified as well as crude samples (e.g. cell lysate) and contains material sufficient for 3840 single-point MST measurements. RED dyes are suited for Monolith instruments with a RED detector (Nano and Pico) and Dianthus instruments. Store at -20 °C.

Monolith Protein Labeling Kits

Catalog #

MO-L001

Product

Monolith Protein Labeling Kit RED-NHS (Amine Reactive)

Description

Monolith Protein Labeling Kits contain all required labeling and dye removal reagents. The dye carries a reactive NHS-ester group that reacts with primary amines (lysine residues) to form a covalent bond. The kit is optimized for proteins with a molecular weight of more than 5 kDa and concentrations between 2 and 20 µM. The RED dye is suited for Monolith NT.115 series and Monolith NT.Automated instruments with a RED detector (Nano and Pico).

MO-L003

Monolith Protein Labeling Kit BLUE-NHS (Amine Reactive)

Monolith Protein Labeling Kits contain all required labeling and dye removal reagents. The dye carries a reactive NHS-ester group that reacts with primary amines (lysine residues) to form a covalent bond. The kit is optimized for proteins with a molecular weight of more than 5 kDa and concentrations between 2 and 20 µM. The BLUE dye is suited for Monolith NT.115 series and Monolith NT.Automated instruments with a BLUE detector.

MO-L004

Monolith Protein Labeling Kit RED-MALEIMIDE (Cysteine Reactive)

Monolith Protein Labeling Kits contain all required labeling and dye removal reagents. The dye carries a reactive maleimide group that reacts with cysteine residues to form a covalent bond. The kit is optimized for proteins with a molecular weight of more than 5 kDa and concentrations between 2 and 20 µM. The RED dye is suited for Monolith NT.115 series and Monolith NT.Automated instruments with a RED detector (Nano and Pico).

MO-L006

Monolith Protein Labeling Kit BLUE-MALEIMIDE (Cysteine Reactive)

Monolith Protein Labeling Kits contain all required labeling and dye removal reagents. The dye carries a reactive maleimide group that reacts with cysteine residues to form a covalent bond. The kit is optimized for proteins with a molecular weight of more than 5 kDa and concentrations between 2 and 20 µM. The BLUE dye is suited for Monolith NT.115 series and Monolith NT.Automated instruments with a BLUE detector.

MO-L008

Monolith His-Tag Labeling Kit RED-tris-NTA

The Monolith His-tag Labeling Kit is used for the site-specific, purification-free labeling of small amounts of His-tagged proteins with our RED dye. This kit can be used for the labeling of any protein or peptide carrying a polyhistidine-tag (His-tag). The kit contains everything required to perform labeling for 500 single-point MST measurements. Labeling can be completed in 30 min, no removal of excess dye is required.

Assay Development Kits

Catalog #

NT-B001

Product

Buffer Exploration Kit

Description

Your mission is to find the right buffer conditions for biophysical interaction assays, protein stability, purification, and storage. This kit will help you with your MST and TRIC assay development. Start your buffer exploration with this 96 deep-well plate containing 1 mL of each buffer condition per well.

MO-X001

Monolith Explorer Kit – Mission to Mars

The goal of this mission is to get your assay development going. We’ve packed everything you’ll need to perform one independent labeling reaction for proteins and peptides with RED-NHS and RED-tris-NTA 2nd Generation dyes. Includes dyes, dye removal reagents, and 60 premium capillaries. Store contents at room temperature, 4 °C and -20 °C as required.

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Monolith Capillaries

Catalog #

MO-AK002

Product

Monolith NT.Automated Capillary Chips

Description

High precision glass capillaries for Monolith NT.Automated. Includes 16 chips, 24 capillaries per chip. Enough chips to measure 384 data points. Store at room temperature.

MO-AK005

Monolith NT.Automated Premium Capillary Chips

High precision glass capillaries for Monolith NT.Automated, covalently coated with a specially designed polymer. Includes 16 chips, 24 capillaries per chip. Enough chips to measure 384 data points. Store at room temperature.

MO-AZ002

Monolith NT.Automated LabelFree Capillary Chips

High precision glass capillaries for label-free assays in Monolith NT.Automated. Includes 16 chips, 24 capillaries per chip. Enough chips to measure 384 data points. Store at room temperature.

MO-AZ005

Monolith NT.Automated LabelFree Premium Capillary Chips

High precision glass capillaries for label-free assays in Monolith NT.Automated, covalently coated with a specially designed polymer. Includes 16 chips, 24 capillaries per chip. Enough chips to measure 384 data points. Store at room temperature.

MO-K022

Monolith NT.115 Capillaries

High precision capillary geometry, physically treated to obtain high quality surface properties. 1000 capillaries for the Monolith NT.115 systems are included.

MO-K025

Monolith NT.115 Premium Capillaries

High precision capillary geometry, covalently coated with a specially designed polymer to prevent surface adsorption of molecules. 200 Premium Capillaries for the Monolith NT.115 systems are included.

MO-Z022

Monolith NT.LabelFree Capillaries

High precision capillary geometry, physically treated to obtain high quality surface properties and low background signal. 200 capillaries for Monolith NT.LabelFree system are included.

MO-Z025

Monolith NT.LabelFree Premium Capillaries

High precision capillary geometry, covalently coated with a specially designed polymer to prevent surface adsorption of molecules. 200 Premium Capillaries for the NT.LabelFree instruments are included.

MO-MK025

Monolith Premium Capillary Chips

Premium Capillary Chips for Monolith instruments. The capillary surface is covalently coated with a dense brush of a specially designed polymer to keep sticky proteins free in solution for analysis. Includes 2 boxes, each containing 8 chips of 24 capillaries each. To be used with the Monolith Premium Capillary Chip Lid (CAT# MO-T022). Not suitable for Monolith NT.115.

MO-MZ025

Monolith LabelFree Premium Capillary Chips

Premium LabelFree Capillary Chips for Monolith LabelFree instruments. The capillary surface is covalently coated with a dense brush of a specially designed polymer to keep sticky proteins free in solution for analysis. Includes 2 boxes, each containing 8 chips of 24 capillaries each. To be used with the Monolith Premium Capillary Chip Lid (CAT# MO-T022). Not suitable for Monolith NT.115.

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Monolith Accessories

Catalog #

MO-T001

Product

Premium Capillary Tray Monolith NT.115 Series

Description

Premium Capillary Tray for up to 16 capillaries for the Monolith NT.115 and NT.115Pico systems.

MO-T002

Premium Capillary Tray Monolith NT.LabelFree

Premium Capillary Tray for up to 16 capillaries for the Monolith NT.LabelFree system.

MO-T021

Premium Capillary Tray Monolith

Additional capillary tray for loading samples for Monolith measurements.

MO-T022

Monolith Premium Capillary Chip Lid

This additional capillary chip lid is specifically designed for Monolith and is required to employ Monolith Capillary Chips in the instrument. Suitable for Monolith and Monolith LabelFree Premium Capillary Chips. Not suitable for Monolith NT.115 or Monolith NT.LabelFree.

NT-AT100

Capillary Chip Filling Station

Facilitates manual filling of capillary chips from microtiter plates or from individual tubes.

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