Nucleic Acids

Nucleic acids are macromolecules that store and translate the genetic information of an organism. Since they are essential in virtually all kinds of cellular processes, they are also involved in various interactions with other molecules. For a typical TRIC assay investigating protein-DNA or protein-RNA interactions, it can be most beneficial to use a nucleic acid that is terminally labeled during oligonucleotide synthesis with extrinsic Fluorophores, such as Cy5.