Why choose Prometheus for protein stability characterization?

Get precise, quantitative results early on from discovery to validation and production. Use Prometheus to generate precise unfolding temperatures (Tm and Tonset), size analysis (Tsize and rH), critical denaturant concentrations (Cm), free folding energy (ΔG and ΔΔG), and aggregation results (Tagg). Be confident about moving forward with the right choice every step along the way.

How does Prometheus compare to other systems?

Prometheus Panta

Performs simultaneous measurements with the same samples throughout the entire run

So you gain a deeper understanding of your molecule’s behavior when correlating your conformational and colloidal stability results.


Generates precise, high-resolution data and reliable results every time

Get the kind of stability data you need to clearly see even tiny differences between your molecules and makes it easier to decide which candidates are best to work with moving forward


Gives you a choice of throughput, and then choose manual or automated

Because characterizing stability at different checkpoints in your workflow calls for flexible throughput


Measures label-free under native conditions

Prometheus detects intrinsic fluorescence so you don’t have to introduce dyes and risk interference. And measuring in any buffer means little or no sample prep.

Scientists who require precise results trust Prometheus


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