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Choose the software package you need to get the most out of your Prometheus Panta

Software that gets you up and running in no time

Prometheus software is designed to help you hit the ground running with your stability experiments. Design and execute multi-parameter stability experiments with a few clicks, and customize your annotations using Control software. And when it’s time to make decisions with your data, Analysis software makes it easy to toggle which parameters you use and rank for selection – all with a clean and intuitive user interface that makes identifying stable proteins a breeze.

Design and run all of your experiments with ease

Become an expert right out of the box with intuitive software for your protein stability characterizations. Assay setup requires 3 quick steps and the selection of a few experimental settings. While your experiment is running, label your samples then sit back while the results are generated for you. When the experiment is over, take a quick glance at results right away, or load up the next batch of samples.

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Panta Control

Assistance with your assay setup

Panta.Control automatically detects the capillaries that contain protein sample. Select the experiment type you want to run, and it will guide you through the set up process. The software monitors your experiment and if something’s a bit off, it will alert you with a warning message.

Collect lots of stability information in a single experiment

Collect stability data from nanoDSF, backreflection, and DLS technologies from the same samples, in the same run, along an entire thermal ramp. Calculate Tm, Tonset, Tturbidity, Tsize, and Tscattering automatically with built-in algorithms.

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Set up additional experiments within the same file

Running multiple batches of samples? Want to run self-association experiments prior to your thermal ramp? Doing accelerated stability studies? Add all those experiments into a single tabbed control file for easy organization and documentation of experiment progress.

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Panta AutoControl

Unprecedented throughput for your protein stability screening

Panta + Robotic Autosampler enables stability measurements on up to 1536 replicates without having to reload your samples. Set up four 384-well plates with your candidates of interest, import your well layout, and you’re ready to go.

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Get more data out of more samples

Panta AutoControl helps you set up multiple experiments on the same samples, so you get more information for your projects. Choose which experiments to run – mix and match, or run the same measurements on all your samples.

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Built-in safety control

To protect the safety of your labmates, as well as the integrity of your robotics, the Robotic Autosampler won’t run if the enclosure is open. Plus, before you run your experiment, clear software prompts help you check that your samples and materials are loaded correctly. The result is a high-throughput instrument that requires minimal training for safe use.

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Design and run all of your experiments with ease

Panta Analysis software is designed for when it’s time to deep dive into your results. It provides powerful analysis features, including auto-merging, the ability to focus on regions of interest, and fully customizable templates of stability parameters.

Stability analysis software allows you to:
  • Merge data generated from your Prometheus Panta system to pinpoint trends and provide statistical analysis of your merged replicate data sets
  • Select how you want to group and organize the information so you get conclusions faster
  • View all your data or highlight a subset of the information to monitor trends
  • Save your preferred settings and evaluation parameters as a template or reference and easily access it for your next run
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Panta Analysis

Combine data from multiple runs

Whether you’re analyzing data from a single run or comparing multiple data sets, Panta.Analysis has your answers. Merge all your data, view the results, and get statistical analysis on your replicates.

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Customize the way you collate data

Get you a jump on data interpretation with a ton of parameters to display and rank. Choose to display only those that help you determine which constructs or conditions are having an impact on your protein’s stability.

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Make templates to standardize your analysis

Generate custom templates to tailor how you view your experimental data. Save export settings, references, and analysis templates as a library of settings for you or your labmates to use for future experiments.

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Spend less time double-checking your results

All your data is analyzed with built-in quality checks and data-fitting. Outliers are automatically flagged and removed from results, and data is automatically fit with both regularization and cumulants fits to provide insight on your samples.

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